I. Sayago, M. J. Fernández, J. L. Fontecha, M. C. Horrillo, E. Terrado, A. Seral-Ascaso, E. Muñoz
Spanish Conference on Electron Devices, pp. 127-130
A Love-wave device combined with a microfluidic chip of PDMS has been developed to detect biological warfare agents (BWA) in liquid media. It has been tested with the realization of two immunoassays: in the first one the bacteriophage M13 has been detected through the mouse monoclonal antibody, anti-M13 (AM13) and in the second one the detection has been carried out by means of the immunoreaction of the rabbit immunoglobulin (Rabbit IgG) with the goat anti-rabbit polyclonal antibody (GAR). The detections have been performed in a dynamic mode (continuous flow-through) in order to obtain a short response time. Different concentrations have been detected with a fast response and a good discrimination among them.
