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Elvira Segura, Luis

Ultrasound for Liquid Analysis and Bioengineering (ULAB)
Científico titular
https://orcid.org/0000-0001-8748-966X
Publications
Projects
438777 / 438806
913 917 503
Contact

My research activity is dedicated to the study of the propagation of ultrasound mechanical waves in different media and materials, mainly in liquids, as well as the development of instrumentation for the analysis of processes in the field of health, microbiology, biochemistry. and food science. This has led me to study different phenomena such as microbial growth, its associated metabolism or the enzymatic reactions induced both by pure enzymes and by enzymes of the microorganisms themselves; from a new point of view: that of the mechanical properties of biological media. In this way, a new sensory dimension is provided to processes which were traditionally analysed using electromagnetic (microscopy, spectrophotometry, etc.) and chemical techniques. This work has involved developing new instrumentation based on ultrasound to adapt conventional acoustic characterization techniques to the requirements of biological tests.

On the other hand, and in the health area, I work on the development of new diagnostic techniques based on ultrasound imaging. Some of these techniques are based on the measurement of the concentration of cells, from the analysis of ultrasound scattering coming from them at high frequencies (> 15MHz). This research line allowed introducing myself into QUS (Quantitative UltraSound) methodologies. These techniques provide quantitative data from images of biological fluids and tissues, by using spectral, envelope statistics and deep learning algorithms.

The similarity of mathematical formulations and instrumentation made it possible to combine these applications with others in the field of non-destructive testing in civil structures (energy sector, aeronautical sector, etc.), mainly, through guided waves analysis.

In this context of applied research, there are three guidelines that articulate my way of projecting and carrying out the work. The first consists of generating new ideas and knowledge from the theoretical and experimental research, seeking new connections between physical and biological phenomena based on the analysis of the interaction of mechanical waves with the environment. The second of these guidelines is the transfer of this knowledge to our society through the development of new technologies and patents, collaborations with the business sector and participation in the creation of technology-based companies. The third consists of the training of new researchers either through doctoral, master and grade thesis supervision; the training of university students through masters courses and, in general, the education of the public through scientific outreach activities.

 

 

Proyectos de investigación recientes

Cutting-Edge Machine Learning Algorithms for Enhanced Signal Processing in High-Frequency Ultrasonic Imaging of cellular processes (MAHUI)
Integrated approach to assess the levels and impact of cONtaminants of Emerging concern on BLUE health and biodiversity modulated by climate change drivers
High resolution multimodal ultrasound imaging in cerebrovascular diseases. A preclinical approach towards new translational applications
Mechanical characterization of biological fluids and tissues at cellular resolution range

Publicaciones recientes

FOCALIZACIÓN DE APERTURA SINTÉTICA EN SISTEMAS MONOTRANSDUCTOR PARA AUMENTAR LA PROFUNDIDAD DE FOCO EN IMAGENES ULTRASÓNICAS DE ALTA FRECUENCIA
Libros de Actas - Tecniacústica 2023 - Cuenca , pp. 892-895
Conformador de imagen ultrasónica basado en redes neuronales
Libro de Actas - Tecniacútica 2023 - Cuenca
Estimation of the concentration of particles in suspension based on envelope statistics of ultrasound backscattering
Ultrasonics Vol 116, 106501, septiembre 2021
New methods for diagnostic tools and prevention
CSIC Scientific Challenges: towards 2030, vol. 4, Challenges in Biomedicine & Health, Challenge 8. Editorial CSIC, 2021
A New Methodology for the Assessment of Very Low Concentrations of Cells in Serous Body Fluids Based on the Count of Ultrasound Echoes Backscattered From Cells
IEEE Transactions in Ultrasonics, Ferroelectrics and Frequency control, Vol 68, No 5, pp 1580-1592, mayo 2021
Acoustics and Non Destructive Evaluation (DAEND)
  • Environmental Acoustics (GAA)
  • G Carma: Materials Characterization by Non Destructive Evaluation
  • ULAB, Ultrasounds for Liquid Analysis and Bioengineering
Information and Communication Technologies (TIC)
  • Cybersecurity and Privacy Protection Research Group (GiCP)
  • Research group on Cryptology and Information Security (GiCSI)
    • Quantum Communications Laboratory (LCQE)
  • Multichannel Ultrasonic Signal Processing Group (MUSP)
Sensors and Ultrasonic Systems (DSSU)
  • Ultrasonic Systems and Technologies (USTG)
  • Nanosensors and Smart Systems (NoySi)
  • Ultrasonic Resonators for cavitation and micromanipulation (RESULT)
  • Advanced Sensor Technology (SENSAVAN)
  • Quantum Electronics (QE)
Laboratorios
  • Laboratorio de Acústica
  • Laboratorio de Metrología Ultrasónica Médica (LMUM)
  • Laboratorio de Comunicaciones Cuánticas
  • Laboratory for International Collaboration in Advanced Biophotonics Imaging

Instituto de Tecnologías Físicas y de la Información Leonardo Torres Quevedo  - ITEFI
C/ Serrano, 144. 28006 - Madrid • Tel.: (+34) 91 561 88 06  Contacto  •  Intranet
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