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Materiales magnéticos nano y microestructurados integrados en miniaturizados e inteligentes sistemas analíticos para detectar enfermedades mediante el aliento

  • Proyecto

This proposal intends to continue the fruitful collaboration established thanks to the project RTI2018-095856-B-C21 and B-C22 among experts of the Institute of Applied Magnetism of the Complutense University (IMA-UCM) in the synthesis of micro and nano magnetic materials, with proven possibilities of application in fields of interest such as sensors and magnetic nanoheaters, together with experts of the Group of Technology of Advanced Sensors (SENSAVAN) of the Institute of Physical and Information Technologies (ITEFI-CSIC) internationally recognized in the field of gas sensors and their applications.

The main objective of the proposed research is the development of new magnetic materials to allow both optimizing the response of current gas sensors and the development of new wireless gas sensors based on magnetic transductors, with applications in the field of biomedicine. The experiments will be focused in the development of sensing platforms for detecting exhaled breath chemical markers related to certain diseases. For this purpose, two routes based in the previous results and shared experience, must be addressed. The first one is the optimization of current gas sensors by means of magnetic nanoparticles where it should be distinguished between resistive and spin wave sensors. In this case, it will be used materials based on a few layer graphene oxide decorated with a combination of metal and magnetic nanoparticles where besides the heating capacity of the nanoparticles is intended to be used as a signal amplifier. In the case of spin wave sensors, iron oxide and manganite nanoparticles will allow the detection of both reducing and oxidizing gases. The second main objective would be, on one side, improving sensitivity and detectability of wireless gases sensors based on magnetoelastic resonance of amorphous magnetic microwires by means of designing new geometrical configurations of sensing elements, improving functionalization layers and developing the adequate electronic and the instrumentation devices to achieve at least a TRL4. This objective also includes the analysis of the capacities for the detection of gases by giant magnetoimpedance of microwires in the microwave range. In case of achieving sensors with detection capacity of interest in the market, a patent will be made in this regard. Once this goal is achieved, the next step will be to obtain financing for validation in a clinical setting and, if successful, a searching for potential investors interested in the technology with which the patent could be licensed, and with a contract signed would begin the technology transfer to reach the scaling. Proposed companies and hospitals with interest in the project are: Gnanomat, Owlstone Medical, Hospital de Alcorcón, Ruber Internacional, Ikerlan, Sener and Thermo Pisher Scientific.

In case of achieving sensors with detection capacity of interest in the market, a patent will be made in this regard. Once this goal is achieved, the next step will be to obtain financing for validation in a clinical setting and, if successful, a searching for potential investors interested in the technology with which the patent could be licensed, and with a contract signed would begin the technology transfer to reach the scaling. Proposed companies and hospitals with interest in the project are: Gnanomat, Owlstone Medical, Hospital de Alcorcón, Ruber Internacional, Ikerlan, Sener and Thermo Pisher Scientific.

IMA-UCM, ITEFI-CSIC

Datos del proyecto

MATMAGSEN
Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023
PID2021-123112OB-C21
Investigador principal
Otros participantes ITEFI
M. Carmen Horrillo Güemes
Other personnel involved:

Pilar Marín Palacios
Investigadora principal (UCM)

Inicio: 09-01-2022 Finalización: 31-08-2025
SENSAVAN
Departamento de Acústica y Evaluación No Destructiva (DAEND)
  • GAA: Grupo de Acústica ambiental
  • G CARMA: Grupo de Caracterización de materiales mediante evaluación no destructiva
  • ULAB: Ultrasonidos para el análisis de líquidos y bioingeniería
Departamento de Tecnologías de la Información y Las Comunicaciones (DTIC)
  • GiCP: Grupo de investigación en Ciberseguridad y Protección de la Privacidad
  • GICSI: Grupo de investigación en Criptología y Seguridad de la Información
    • LCQE: Laboratorio de Comunicaciones Cuánticas
  • PSUM: Grupo de Procesamiento de Señal en sistemas Ultrasónicos Multicanal
Departamento de Sensores y Sistemas Ultrasónicos (DSSU)
  • GSTU: Grupo de Sistemas y tecnologías ultrasónicas
  • NoySI: Grupo de Nanosensores y Sistemas Inteligentes
  • RESULT: Resonadores ultrasónicos para cavitación y micromanipulación
  • SENSAVAN: Grupo de Tecnología de Sensores Avanzados
  • QE: Electrónica Cuántica
Laboratorios
  • Laboratorio de Acústica
  • Laboratorio de Metrología Ultrasónica Médica (LMUM)
  • Laboratorio de Comunicaciones Cuánticas
  • Laboratory for International Collaboration in Advanced Biophotonics Imaging

Instituto de Tecnologías Físicas y de la Información Leonardo Torres Quevedo  - ITEFI
C/ Serrano, 144. 28006 - Madrid • Tel.: (+34) 91 561 88 06  Contacto  •  Intranet
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