Las principales líneas en desarrollo son:
- Desarrollo de plataformas lab-on-chip para separación celular y de elementos biomarca- dores en muestras de sangre y otros fluidos biológicos.
- Aplicación de ultrasonidos de baja intensidad en tumores y phantoms de tumor y estroma para su cacterización y tratamiento en procesos cancerígenos.
Nuestras plataformas lab-on-chip para la manipulación de partículas
SU-8 layer containig the channel over a substrate to perform the mass transfer and, with it, the particle or cell separation.
Particle collection at the center of the channel at 500KHz : ICU’07 Vienna, Biotech 2006
Applications of Ultrasounds for particle manipulation
Acoustic Agglomeration in Aerosols
Particles interact under acoustic waves giving rise to acoustic agglomeration at certain hydrodynamic-acoustic conditions.
Mechanisms governing the particle interactions induced by Ultrasounds can be analyzed observing the particles during the application of the acoustic field. The particle trajectories can be reconstructed from their bright traces filmed during their approaching processes subjected to horizontal standing waves:
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Numerical prediction of two attraction processes developed at f=3kHz |
I. Gonzalez et al. J. Aerosol Sci. Vol. 31, No. 12, pp. 1461-1468 (2000) |
A whole attraction process between two particles |
Sinusoidal lateral displacements of the particles during their attraction process before their collision |
I. González et al. / Aerosol Science 34 (2003) 1611–1631 |